{"id":2124,"date":"2021-09-10T11:00:02","date_gmt":"2021-09-10T11:00:02","guid":{"rendered":"https:\/\/scisoup.org\/in\/?p=2124"},"modified":"2026-07-14T11:09:16","modified_gmt":"2026-07-14T11:09:16","slug":"blood-stem-cell-learns-from-its-environment-how-to-boost-the-immunity-study","status":"publish","type":"post","link":"https:\/\/scisoup.org\/in\/2021\/09\/10\/blood-stem-cell-learns-from-its-environment-how-to-boost-the-immunity-study\/","title":{"rendered":"Blood Stem Cell Learns From Its Environment How To Boost The Immunity: Study"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-post\" data-elementor-id=\"2124\" class=\"elementor elementor-2124\">\n\t\t\t\t<div class=\"elementor-element elementor-element-6a182722 e-flex e-con-boxed e-con e-parent\" data-id=\"6a182722\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-35b47ca2 e-con-full e-flex e-con e-child\" data-id=\"35b47ca2\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-58155fdd elementor-widget elementor-widget-sina_post_title\" data-id=\"58155fdd\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"sina_post_title.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<h2 class=\"sina-post-title\">Blood Stem Cell Learns From Its Environment How To Boost The Immunity: Study<\/h2><!-- .sina-post-title -->\r\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-3a2476bb e-grid e-con-full e-con e-child\" data-id=\"3a2476bb\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t<div class=\"elementor-element elementor-element-482e753f e-con-full e-flex e-con e-child\" 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decoding=\"async\" width=\"1024\" height=\"614\" src=\"https:\/\/scisoup.org\/in\/wp-content\/uploads\/2026\/07\/10-09-2021-1024x614.png\" class=\"attachment-large size-large wp-image-2125\" alt=\"\" srcset=\"https:\/\/scisoup.org\/in\/wp-content\/uploads\/2026\/07\/10-09-2021-1024x614.png 1024w, https:\/\/scisoup.org\/in\/wp-content\/uploads\/2026\/07\/10-09-2021-300x180.png 300w, https:\/\/scisoup.org\/in\/wp-content\/uploads\/2026\/07\/10-09-2021-768x461.png 768w, https:\/\/scisoup.org\/in\/wp-content\/uploads\/2026\/07\/10-09-2021.png 1250w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-4ae9e94 elementor-widget elementor-widget-text-editor\" data-id=\"4ae9e94\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p><strong>BY RATNESHWAR THAKUR<\/strong><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element 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class=\"elementor-icon elementor-social-icon elementor-social-icon-linkedin elementor-repeater-item-6fee99d\" href=\"https:\/\/www.linkedin.com\/in\/ratnesh-thakur\/\" target=\"_blank\">\n\t\t\t\t\t\t<span class=\"elementor-screen-only\">Linkedin<\/span>\n\t\t\t\t\t\t<svg aria-hidden=\"true\" class=\"e-font-icon-svg e-fab-linkedin\" viewBox=\"0 0 448 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M416 32H31.9C14.3 32 0 46.5 0 64.3v383.4C0 465.5 14.3 480 31.9 480H416c17.6 0 32-14.5 32-32.3V64.3c0-17.8-14.4-32.3-32-32.3zM135.4 416H69V202.2h66.5V416zm-33.2-243c-21.3 0-38.5-17.3-38.5-38.5S80.9 96 102.2 96c21.2 0 38.5 17.3 38.5 38.5 0 21.3-17.2 38.5-38.5 38.5zm282.1 243h-66.4V312c0-24.8-.5-56.7-34.5-56.7-34.6 0-39.9 27-39.9 54.9V416h-66.4V202.2h63.7v29.2h.9c8.9-16.8 30.6-34.5 62.9-34.5 67.2 0 79.7 44.3 79.7 101.9V416z\"><\/path><\/svg>\t\t\t\t\t<\/a>\n\t\t\t\t<\/span>\n\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-140d6848 elementor-widget elementor-widget-heading\" data-id=\"140d6848\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">IISER Mohali based new study suggests the hematopoietic niche (micro-environment of stem cells) acts as a sensor that can perceive the pathophysiological state of the organism and divert the normal blood cell development to the emergency mode for the protection of the body from infections.\n<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-3406209a elementor-widget elementor-widget-text-editor\" data-id=\"3406209a\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p>T<span style=\"font-weight: 400;\">he human body regularly encounters various pathogens; therefore, the body has specialized combat systems or immune systems that help to neutralize infections regularly. One of those combat systems is at the level of hematopoiesis \u2013 a process through which the body manufactures cellular components of blood and blood plasma, including immune cells. How these blood cells forming machinery switch quickly from developmental process to combat mode to take care of the immune challenges like bacterial infections &#8211; are not fully understood.<\/span><br style=\"font-weight: 400;\" \/><br style=\"font-weight: 400;\" \/><span style=\"font-weight: 400;\">New research from Dr. Lolitika Mandal\u2019s lab has worked out the underpinnings of this complex interplay between immune challenge and mounting a successful defense using a Drosophila model. Parvathy, Nidhi and Aditya, Mandal lab members discovered the role of a molecule namely \u2018Relish\u2019, in the microenvironment that serves as the rudder for controlling immune cell activation and maturation during infection. The loss of Relish from stem cell microenvironment\/niche increases the rate of mature blood cells production to fight out the infection. The results published in the \u2018eLife\u2019 journal demonstrate Relish as a crucial player in immunity and developmental hematopoiesis.<\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-481be15c elementor-widget elementor-widget-text-editor\" data-id=\"481be15c\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p>\u201cWe have shown that hematopoietic niche acts as a sensor that can perceive the pathophysiological state of the organism and divert the normal blood cell development to emergency mode,\u201d says Prof. Lolitika Mandal, Study leader and Developmental Biologist at IISER, Mohali.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-1107b26 elementor-widget elementor-widget-text-editor\" data-id=\"1107b26\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p>Earlier, Prof. Mandal\u2019s lab has worked out many different details in the blood stem cell field using Drosophila genetics. For this study, they performed a massive genome widescreen. Using a careful analysis they further found stem cell niche to be vital in the development, maintenance and activation of stem\/progenitor blood cells during infection. The combined approach of genetics, molecular biology and state of the art microscopy, effectively showed Relish to be specifically expressed by stem cell niche or home environment. In an uninfected individual, Relish in the niche keeps the na\u00efve cells calm. However, the expression of Relish extinguishes when challenged by bacterial infection. This \u2018no Relish\u2019 signals cells to mature rapidly and prepare for fight against infection.<br \/><br \/>Interestingly, in the absence of bacterial infection, niche cells continue to maintain Relish levels. This, according to Prof. Mandal and colleagues, is vital for the normal development of immune system in Drosophila. These findings, in summary, show the dual role of Relish, which is a close relative of NF-kB protein found in humans.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-2d680af elementor-widget elementor-widget-image\" data-id=\"2d680af\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"1024\" height=\"614\" src=\"https:\/\/scisoup.org\/in\/wp-content\/uploads\/2026\/07\/10-09-2021-01-1024x614.png\" class=\"attachment-large size-large wp-image-2127\" alt=\"\" srcset=\"https:\/\/scisoup.org\/in\/wp-content\/uploads\/2026\/07\/10-09-2021-01-1024x614.png 1024w, https:\/\/scisoup.org\/in\/wp-content\/uploads\/2026\/07\/10-09-2021-01-300x180.png 300w, https:\/\/scisoup.org\/in\/wp-content\/uploads\/2026\/07\/10-09-2021-01-768x461.png 768w, https:\/\/scisoup.org\/in\/wp-content\/uploads\/2026\/07\/10-09-2021-01.png 1250w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-48a0fc1 elementor-widget elementor-widget-text-editor\" data-id=\"48a0fc1\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p>Mandal laboratory believes that the capacity of the stem cell niche to sense the physiological state of an animal and thereafter dictate the stem or progenitor cell fate can be exploited for niche based therapeutic interventions in coming years.<br \/><br \/>The research group included Parvathy Ramesh, Nidhi Sharma Dey, Aditya Kanwal, Sudip Mandal and Lolitika Mandal from the Indian Institute of Science Education and Research (IISER), Mohali.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-3f5413c elementor-widget elementor-widget-text-editor\" data-id=\"3f5413c\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p><strong>Journal Reference:<\/strong><br \/><a href=\"https:\/\/doi.org\/10.7554\/eLife.67158\" target=\"_blank\" rel=\"noopener\">Relish plays a dynamic role in the niche to modulate Drosophila blood progenitor homeostasis in development and infection<\/a><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-7381b09c e-con-full e-flex e-con e-child\" data-id=\"7381b09c\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-483882f8 section-title-style-style2 title-three-line meta-visibility-show title_position_default title_hover_border_default img_hover_animation_default meta_position_default tpg-category-position-default grid-hover-overlay-type-always tpg-el-box-border-enable tpg-border-bottom-disable elementor-widget elementor-widget-tpg-list-layout\" data-id=\"483882f8\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"tpg-list-layout.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\n        <div class=\"rt-container-fluid rt-tpg-container tpg-el-main-wrapper list-layout1-main \"\n             data-sc-id=\"elementor\"\n             id=\"rt-tpg-container-3731918964\"\n             data-layout=\"list-layout1\"\n             data-grid-style=\"tpg-even\"\n             data-el-settings=''\n             data-el-query=''\n             data-el-path=''\n        >\n\t\t\t            <div class='tpg-header-wrapper '>\n\t\t\t\t\n\t\t<div class=\"tpg-widget-heading-wrapper rt-clear heading-style2 \">\n\t\t\t<span class=\"tpg-widget-heading-line line-left\"><\/span>\n\t\t\t<h2 class='tpg-widget-heading'>\n\t\t\t\n\t\t\t\t\t\t\t\t\t<span>\n\t\t\t\t\t\tTOP STORIES\t\t\t\t\t<\/span>\n\t\t\t\t\t\n\t\t\t\t\t\t\t<\/h2>\t\t\t<span class=\"tpg-widget-heading-line line-right\"><\/span>\n\n\t\t\t\n\t\t<\/div>\n\n\t\t\n\t\t            <\/div>\n\n            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href=\"https:\/\/scisoup.org\/in\/category\/latest\/\">Latest<\/a><span class=\"rt-separator\">,<\/span><a class=\"recent-posts\" href=\"https:\/\/scisoup.org\/in\/category\/recent-posts\/\">Recent Posts<\/a>\t\t\t<\/span>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\n\t\t\t\t\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t<\/div>\n<\/div>\n\n<div class=\"rt-col-md-12 rt-col-sm-12 rt-col-xs-12 default rt-list-item rt-grid-item\" data-id=\"2042\">\n\t<div class=\"rt-holder tpg-post-holder \">\n\t\t<div class=\"rt-detail rt-el-content-wrapper\">\n\t\t\t\t\t\t\t<div class=\"rt-img-holder tpg-el-image-wrap has-thumbnail\">\n\t\t\t\t\t<a data-id=\"2042\" href=\"https:\/\/scisoup.org\/in\/2026\/07\/12\/scisoup-lab-stories-conversations-with-stem-leaders\/\" class=\"tpg-post-link\" target=\"_self\">\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/scisoup.org\/in\/wp-content\/uploads\/2026\/07\/SCISOUP-FLYER-BANNER-150x150.png\"\n\t\t\t\t\t\t\t class=\"rt-img-responsive\"\n\t\t\t\t\t\t\t width=\"150\"\n\t\t\t\t\t\t\t height=\"150\"\n\t\t\t\t\t\t\t alt=\"SciSoup Lab Stories: Conversations with STEM Leaders\">\n\t\t\t\t\t\t\n\t\t\t\t\t\t\t\n\t\t<\/a>\n\t\t\t\t<div class=\"overlay grid-hover-content\"><\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\n\t\t\t<div class=\"post-right-content\">\n\t\t\t\t<div class=\"entry-title-wrapper\"><h3 class=\"entry-title\"><a data-id=\"2042\" href=\"https:\/\/scisoup.org\/in\/2026\/07\/12\/scisoup-lab-stories-conversations-with-stem-leaders\/\" class=\"tpg-post-link\" target=\"_self\">SciSoup Lab Stories: Conversations with STEM Leaders<\/a><\/h3><\/div>\n\t\t\t\t\t\t\t\t\t<div class=\"post-meta-tags rt-el-post-meta\">\n\t\t\t\t\t\t\t\t\t<span class=\"date\">\n\t\t\t\t<i class=\"tpg-flaticon-calendar \"><\/i>\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/scisoup.org\/in\/2026\/07\/12\/\">\n\t\t\t\t\tJuly 12, 2026\t\t\t\t<\/a>\n\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t<span class=\"categories-links\">\n\t\t\t\t<i class=\"tpg-flaticon-folder \"><\/i><a class=\"articles\" href=\"https:\/\/scisoup.org\/in\/category\/articles\/\">Articles<\/a><span class=\"rt-separator\">,<\/span><a class=\"lab-stories\" href=\"https:\/\/scisoup.org\/in\/category\/lab-stories\/\">Lab Stories<\/a><span class=\"rt-separator\">,<\/span><a class=\"latest\" href=\"https:\/\/scisoup.org\/in\/category\/latest\/\">Latest<\/a><span class=\"rt-separator\">,<\/span><a class=\"spotlight\" href=\"https:\/\/scisoup.org\/in\/category\/spotlight\/\">Spotlight<\/a>\t\t\t<\/span>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\n\t\t\t\t\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t<\/div>\n<\/div>\n\n<div class=\"rt-col-md-12 rt-col-sm-12 rt-col-xs-12 default rt-list-item rt-grid-item\" data-id=\"1954\">\n\t<div class=\"rt-holder tpg-post-holder \">\n\t\t<div class=\"rt-detail rt-el-content-wrapper\">\n\t\t\t\t\t\t\t<div class=\"rt-img-holder tpg-el-image-wrap has-thumbnail\">\n\t\t\t\t\t<a data-id=\"1954\" href=\"https:\/\/scisoup.org\/in\/2026\/07\/02\/science-beyond-boundaries-inspiring-ideas-from-the-37th-mid-year-meeting-of-the-indian-academy-of-sciences\/\" class=\"tpg-post-link\" target=\"_self\">\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/scisoup.org\/in\/wp-content\/uploads\/2026\/07\/Special_and_Public_Lecture_MYM_2026-4-150x150.png\"\n\t\t\t\t\t\t\t class=\"rt-img-responsive\"\n\t\t\t\t\t\t\t width=\"150\"\n\t\t\t\t\t\t\t height=\"150\"\n\t\t\t\t\t\t\t alt=\"Science Beyond Boundaries: Inspiring Ideas from the 37th Mid-Year Meeting of the Indian Academy of Sciences\">\n\t\t\t\t\t\t\n\t\t\t\t\t\t\t\n\t\t<\/a>\n\t\t\t\t<div class=\"overlay grid-hover-content\"><\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\n\t\t\t<div class=\"post-right-content\">\n\t\t\t\t<div class=\"entry-title-wrapper\"><h3 class=\"entry-title\"><a data-id=\"1954\" href=\"https:\/\/scisoup.org\/in\/2026\/07\/02\/science-beyond-boundaries-inspiring-ideas-from-the-37th-mid-year-meeting-of-the-indian-academy-of-sciences\/\" class=\"tpg-post-link\" target=\"_self\">Science Beyond Boundaries: Inspiring Ideas from the 37th Mid-Year Meeting of the Indian Academy of Sciences<\/a><\/h3><\/div>\n\t\t\t\t\t\t\t\t\t<div class=\"post-meta-tags rt-el-post-meta\">\n\t\t\t\t\t\t\t\t\t<span class=\"date\">\n\t\t\t\t<i class=\"tpg-flaticon-calendar \"><\/i>\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/scisoup.org\/in\/2026\/07\/02\/\">\n\t\t\t\t\tJuly 2, 2026\t\t\t\t<\/a>\n\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t<span class=\"categories-links\">\n\t\t\t\t<i class=\"tpg-flaticon-folder \"><\/i><a class=\"articles\" href=\"https:\/\/scisoup.org\/in\/category\/articles\/\">Articles<\/a><span class=\"rt-separator\">,<\/span><a class=\"recent-posts\" href=\"https:\/\/scisoup.org\/in\/category\/recent-posts\/\">Recent Posts<\/a>\t\t\t<\/span>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\n\t\t\t\t\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t<\/div>\n<\/div>\n\n<div class=\"rt-col-md-12 rt-col-sm-12 rt-col-xs-12 default rt-list-item rt-grid-item\" data-id=\"1945\">\n\t<div class=\"rt-holder tpg-post-holder \">\n\t\t<div class=\"rt-detail rt-el-content-wrapper\">\n\t\t\t\t\t\t\t<div class=\"rt-img-holder tpg-el-image-wrap has-thumbnail\">\n\t\t\t\t\t<a data-id=\"1945\" href=\"https:\/\/scisoup.org\/in\/2026\/07\/02\/ultrasound-mechanostimulation-shows-promise-in-selectively-targeting-oral-cancer-cells\/\" class=\"tpg-post-link\" target=\"_self\">\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/scisoup.org\/in\/wp-content\/uploads\/2026\/07\/Ultrasound-cancer-cells2_Siddhesh-Saigaonkar-150x150.jpeg\"\n\t\t\t\t\t\t\t class=\"rt-img-responsive\"\n\t\t\t\t\t\t\t width=\"150\"\n\t\t\t\t\t\t\t height=\"150\"\n\t\t\t\t\t\t\t alt=\"Ultrasound Mechanostimulation Shows Promise In Selectively Targeting Oral Cancer Cells\">\n\t\t\t\t\t\t\n\t\t\t\t\t\t\t\n\t\t<\/a>\n\t\t\t\t<div class=\"overlay grid-hover-content\"><\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\n\t\t\t<div class=\"post-right-content\">\n\t\t\t\t<div class=\"entry-title-wrapper\"><h3 class=\"entry-title\"><a data-id=\"1945\" href=\"https:\/\/scisoup.org\/in\/2026\/07\/02\/ultrasound-mechanostimulation-shows-promise-in-selectively-targeting-oral-cancer-cells\/\" class=\"tpg-post-link\" target=\"_self\">Ultrasound Mechanostimulation Shows Promise In Selectively Targeting Oral Cancer Cells<\/a><\/h3><\/div>\n\t\t\t\t\t\t\t\t\t<div class=\"post-meta-tags rt-el-post-meta\">\n\t\t\t\t\t\t\t\t\t<span class=\"date\">\n\t\t\t\t<i class=\"tpg-flaticon-calendar \"><\/i>\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/scisoup.org\/in\/2026\/07\/02\/\">\n\t\t\t\t\tJuly 2, 2026\t\t\t\t<\/a>\n\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t<span class=\"categories-links\">\n\t\t\t\t<i class=\"tpg-flaticon-folder \"><\/i><a class=\"articles\" href=\"https:\/\/scisoup.org\/in\/category\/articles\/\">Articles<\/a><span class=\"rt-separator\">,<\/span><a class=\"latest\" href=\"https:\/\/scisoup.org\/in\/category\/latest\/\">Latest<\/a>\t\t\t<\/span>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\n\t\t\t\t\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t<\/div>\n<\/div>\n\n<div class=\"rt-col-md-12 rt-col-sm-12 rt-col-xs-12 default rt-list-item rt-grid-item\" data-id=\"1936\">\n\t<div class=\"rt-holder tpg-post-holder \">\n\t\t<div class=\"rt-detail rt-el-content-wrapper\">\n\t\t\t\t\t\t\t<div class=\"rt-img-holder tpg-el-image-wrap has-thumbnail\">\n\t\t\t\t\t<a data-id=\"1936\" href=\"https:\/\/scisoup.org\/in\/2026\/06\/28\/3d-printed-silk-implant-regenerates-cartilage-in-osteoarthritic-rat-knees\/\" class=\"tpg-post-link\" target=\"_self\">\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/scisoup.org\/in\/wp-content\/uploads\/2026\/06\/OA-150x150.png\"\n\t\t\t\t\t\t\t class=\"rt-img-responsive\"\n\t\t\t\t\t\t\t width=\"150\"\n\t\t\t\t\t\t\t height=\"150\"\n\t\t\t\t\t\t\t alt=\"3D-Printed Silk Implant Regenerates Cartilage In Osteoarthritic Rat Knees\">\n\t\t\t\t\t\t\n\t\t\t\t\t\t\t\n\t\t<\/a>\n\t\t\t\t<div class=\"overlay grid-hover-content\"><\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\n\t\t\t<div class=\"post-right-content\">\n\t\t\t\t<div class=\"entry-title-wrapper\"><h3 class=\"entry-title\"><a data-id=\"1936\" href=\"https:\/\/scisoup.org\/in\/2026\/06\/28\/3d-printed-silk-implant-regenerates-cartilage-in-osteoarthritic-rat-knees\/\" class=\"tpg-post-link\" target=\"_self\">3D-Printed Silk Implant Regenerates Cartilage In Osteoarthritic Rat Knees<\/a><\/h3><\/div>\n\t\t\t\t\t\t\t\t\t<div class=\"post-meta-tags rt-el-post-meta\">\n\t\t\t\t\t\t\t\t\t<span class=\"date\">\n\t\t\t\t<i class=\"tpg-flaticon-calendar \"><\/i>\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/scisoup.org\/in\/2026\/06\/28\/\">\n\t\t\t\t\tJune 28, 2026\t\t\t\t<\/a>\n\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t<span class=\"categories-links\">\n\t\t\t\t<i class=\"tpg-flaticon-folder \"><\/i><a class=\"articles\" href=\"https:\/\/scisoup.org\/in\/category\/articles\/\">Articles<\/a><span class=\"rt-separator\">,<\/span><a class=\"lab-stories\" href=\"https:\/\/scisoup.org\/in\/category\/lab-stories\/\">Lab Stories<\/a><span class=\"rt-separator\">,<\/span><a class=\"latest\" href=\"https:\/\/scisoup.org\/in\/category\/latest\/\">Latest<\/a><span class=\"rt-separator\">,<\/span><a class=\"recent-posts\" href=\"https:\/\/scisoup.org\/in\/category\/recent-posts\/\">Recent Posts<\/a>\t\t\t<\/span>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\n\t\t\t\t\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t<\/div>\n<\/div>\n\n<div class=\"rt-col-md-12 rt-col-sm-12 rt-col-xs-12 default rt-list-item rt-grid-item\" data-id=\"1877\">\n\t<div class=\"rt-holder tpg-post-holder \">\n\t\t<div class=\"rt-detail rt-el-content-wrapper\">\n\t\t\t\t\t\t\t<div class=\"rt-img-holder tpg-el-image-wrap has-thumbnail\">\n\t\t\t\t\t<a data-id=\"1877\" href=\"https:\/\/scisoup.org\/in\/2026\/06\/13\/muscle-protein-helps-control-blood-sugar-revealing-new-link-to-diabetes\/\" class=\"tpg-post-link\" target=\"_self\">\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/scisoup.org\/in\/wp-content\/uploads\/2026\/06\/Sam-Mathew-Research-team-150x150.jpg\"\n\t\t\t\t\t\t\t class=\"rt-img-responsive\"\n\t\t\t\t\t\t\t width=\"150\"\n\t\t\t\t\t\t\t height=\"150\"\n\t\t\t\t\t\t\t alt=\"Muscle protein helps control blood sugar, revealing new link to diabetes\">\n\t\t\t\t\t\t\n\t\t\t\t\t\t\t\n\t\t<\/a>\n\t\t\t\t<div class=\"overlay grid-hover-content\"><\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\n\t\t\t<div class=\"post-right-content\">\n\t\t\t\t<div class=\"entry-title-wrapper\"><h3 class=\"entry-title\"><a data-id=\"1877\" href=\"https:\/\/scisoup.org\/in\/2026\/06\/13\/muscle-protein-helps-control-blood-sugar-revealing-new-link-to-diabetes\/\" class=\"tpg-post-link\" target=\"_self\">Muscle protein helps control blood sugar, revealing new link to diabetes<\/a><\/h3><\/div>\n\t\t\t\t\t\t\t\t\t<div class=\"post-meta-tags rt-el-post-meta\">\n\t\t\t\t\t\t\t\t\t<span class=\"date\">\n\t\t\t\t<i class=\"tpg-flaticon-calendar \"><\/i>\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/scisoup.org\/in\/2026\/06\/13\/\">\n\t\t\t\t\tJune 13, 2026\t\t\t\t<\/a>\n\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t<span class=\"categories-links\">\n\t\t\t\t<i class=\"tpg-flaticon-folder \"><\/i><a class=\"articles\" href=\"https:\/\/scisoup.org\/in\/category\/articles\/\">Articles<\/a><span class=\"rt-separator\">,<\/span><a class=\"lab-stories\" href=\"https:\/\/scisoup.org\/in\/category\/lab-stories\/\">Lab Stories<\/a><span class=\"rt-separator\">,<\/span><a class=\"latest\" href=\"https:\/\/scisoup.org\/in\/category\/latest\/\">Latest<\/a><span class=\"rt-separator\">,<\/span><a class=\"recent-posts\" href=\"https:\/\/scisoup.org\/in\/category\/recent-posts\/\">Recent 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class=\"rt-separator\">,<\/span><a class=\"latest\" href=\"https:\/\/scisoup.org\/in\/category\/latest\/\">Latest<\/a><span class=\"rt-separator\">,<\/span><a class=\"recent-posts\" href=\"https:\/\/scisoup.org\/in\/category\/recent-posts\/\">Recent Posts<\/a>\t\t\t<\/span>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\n\t\t\t\t\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t<\/div>\n<\/div>\n\n<div class=\"rt-col-md-12 rt-col-sm-12 rt-col-xs-12 default rt-list-item rt-grid-item\" data-id=\"1321\">\n\t<div class=\"rt-holder tpg-post-holder \">\n\t\t<div class=\"rt-detail rt-el-content-wrapper\">\n\t\t\t\t\t\t\t<div class=\"rt-img-holder tpg-el-image-wrap has-thumbnail\">\n\t\t\t\t\t<a data-id=\"1321\" href=\"https:\/\/scisoup.org\/in\/2025\/05\/06\/scientists-uncover-unusual-cell-division-behind-glioblastomas-deadly-comeback-3\/\" class=\"tpg-post-link\" target=\"_self\">\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/scisoup.org\/in\/wp-content\/uploads\/2026\/01\/06052025-150x150.png\"\n\t\t\t\t\t\t\t class=\"rt-img-responsive\"\n\t\t\t\t\t\t\t width=\"150\"\n\t\t\t\t\t\t\t height=\"150\"\n\t\t\t\t\t\t\t alt=\"Scientists Uncover Unusual Cell Division Behind Glioblastoma\u2019s Deadly Comeback\">\n\t\t\t\t\t\t\n\t\t\t\t\t\t\t\n\t\t<\/a>\n\t\t\t\t<div class=\"overlay grid-hover-content\"><\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\n\t\t\t<div class=\"post-right-content\">\n\t\t\t\t<div class=\"entry-title-wrapper\"><h3 class=\"entry-title\"><a data-id=\"1321\" href=\"https:\/\/scisoup.org\/in\/2025\/05\/06\/scientists-uncover-unusual-cell-division-behind-glioblastomas-deadly-comeback-3\/\" class=\"tpg-post-link\" target=\"_self\">Scientists Uncover Unusual Cell Division Behind Glioblastoma\u2019s Deadly Comeback<\/a><\/h3><\/div>\n\t\t\t\t\t\t\t\t\t<div class=\"post-meta-tags rt-el-post-meta\">\n\t\t\t\t\t\t\t\t\t<span class=\"date\">\n\t\t\t\t<i class=\"tpg-flaticon-calendar \"><\/i>\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/scisoup.org\/in\/2025\/05\/06\/\">\n\t\t\t\t\tMay 6, 2025\t\t\t\t<\/a>\n\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t<span class=\"categories-links\">\n\t\t\t\t<i class=\"tpg-flaticon-folder \"><\/i><a class=\"articles\" href=\"https:\/\/scisoup.org\/in\/category\/articles\/\">Articles<\/a><span class=\"rt-separator\">,<\/span><a class=\"latest\" href=\"https:\/\/scisoup.org\/in\/category\/latest\/\">Latest<\/a><span class=\"rt-separator\">,<\/span><a class=\"recent-posts\" href=\"https:\/\/scisoup.org\/in\/category\/recent-posts\/\">Recent Posts<\/a>\t\t\t<\/span>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\n\t\t\t\t\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t<\/div>\n<\/div>\n            <\/div>\n\n\t\t\t\n        <\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>Blood Stem Cell Learns From Its Environment How To Boost The Immunity: Study SciSoup July 14, 2026 BY RATNESHWAR THAKUR 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