{"id":1473,"date":"2024-02-09T09:17:19","date_gmt":"2024-02-09T09:17:19","guid":{"rendered":"https:\/\/scisoup.org\/in\/?p=1473"},"modified":"2026-06-15T06:59:03","modified_gmt":"2026-06-15T06:59:03","slug":"new-insights-into-lsd1s-critical-role-in-human-brain-cell-development","status":"publish","type":"post","link":"https:\/\/scisoup.org\/in\/2024\/02\/09\/new-insights-into-lsd1s-critical-role-in-human-brain-cell-development\/","title":{"rendered":"New Insights Into LSD1&#8217;s Critical Role In Human Brain Cell Development"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-post\" data-elementor-id=\"1473\" class=\"elementor elementor-1473\">\n\t\t\t\t<div class=\"elementor-element elementor-element-6d86acfc e-flex e-con-boxed e-con e-parent\" data-id=\"6d86acfc\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element 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size-large wp-image-1475\" alt=\"\" srcset=\"https:\/\/scisoup.org\/in\/wp-content\/uploads\/2026\/05\/09-02-2024-1024x614.png 1024w, https:\/\/scisoup.org\/in\/wp-content\/uploads\/2026\/05\/09-02-2024-300x180.png 300w, https:\/\/scisoup.org\/in\/wp-content\/uploads\/2026\/05\/09-02-2024-768x461.png 768w, https:\/\/scisoup.org\/in\/wp-content\/uploads\/2026\/05\/09-02-2024-1536x922.png 1536w, https:\/\/scisoup.org\/in\/wp-content\/uploads\/2026\/05\/09-02-2024-2048x1229.png 2048w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-7d8e276e elementor-widget elementor-widget-text-editor\" data-id=\"7d8e276e\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p><strong>BY RATNESHWAR THAKUR<\/strong><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-1bf053ab e-grid-align-left 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data-id=\"5184e075\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">LSD1, a protein involved in modifying genetic material, plays a crucial role in human brain cell development.\n<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-bff25f8 elementor-widget elementor-widget-text-editor\" data-id=\"bff25f8\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p><b><strong>T<\/strong><\/b><span style=\"font-weight: 400;\">he human brain undergoes a fascinating journey during development. The process of making new brain cells, called neurogenesis, starts with special cells in the brain called neural stem cells. These stem cells first divide and make more of them-selves in a way that&#8217;s like copying. After that, they switch to a different kind of division where they create specific types of cells called neurons, which are the building blocks of the brain. Studies suggest Chromatin regulation plays a critical role in this switch. Any disruptions in its development stages can result in behavioural issues, such as autism and intellectual disability.<\/span><br style=\"font-weight: 400;\" \/><br style=\"font-weight: 400;\" \/><span style=\"font-weight: 400;\">To this end, a research team led by Dr. Bhavana Muralidharan at the Institute for Stem Cell Science and Regenerative Medicine (inStem), Bangalore, India, has been studying to decipher the fundamental role of LSD1, a gene conserved between mice and humans, in human neuronal development.<\/span><br style=\"font-weight: 400;\" \/><br style=\"font-weight: 400;\" \/><span style=\"font-weight: 400;\">Now in a recent study Dr. Muralidharan\u2019s team discovered that LSD1, a protein involved in modifying genetic material, plays a crucial role in human brain cell development. It acts like a conductor, influencing the functions of certain genes related to the nervous system and neurons in human brain cells. This control is important for determining the fate of these cells in the brain. The study, published in the journal &#8216;Stem Cells,&#8217; employs a comprehensive approach, integrating experimental methods like ChIP-seq, RNA-seq, and Histone ChIP-seq data.<\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-5ec72d1 e-con-full e-flex e-con e-child\" data-id=\"5ec72d1\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t<div class=\"elementor-element elementor-element-1e48466f e-con-full e-flex e-con e-child\" data-id=\"1e48466f\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-1a26d538 e-con-full e-flex e-con e-child\" data-id=\"1a26d538\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-65aeb769 elementor-widget elementor-widget-text-editor\" data-id=\"65aeb769\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<div class=\"comment vl\"><div class=\"comment vl\">\u201cOur objective extended to unravelling some of the downstream targets of LSD1, as this knowledge is instrumental in comprehending its molecular function. This understanding holds particular significance due to the fact that mutations in LSD1 result in a rare form of intellectual disability.\u201d says Dr. Bhavana Muralidharan.<br \/><br \/>\u201cThe mouse brain has been invaluable in revealing fundamental features of mammalian neurogenesis, particularly regional patterning. However, our understanding of human-enriched genomic and developmental features crucial for advanced cognition remains limited.\u201d She added. \u201d<\/div><\/div>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-7cc6501e elementor-widget elementor-widget-text-editor\" data-id=\"7cc6501e\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p>Research team observed that LSD1 reduces the activity of genes related to cell adhesion and the extracellular matrix in human neural stem cells. When comparing the methylation marks on histones in the promoter and regulatory regions of LSD1 target genes, researchers observed that these marks are more prevalent at enhancer sites unique to humans, while they are either absent or at low levels in the corresponding mouse locations.<br \/><br \/>Dr. Ishwariya Venkatesh, Senior Scientist &amp; Project Leader at CSIR-Centre for Cellular and Molecular Biology (CCMB), who was not involved in this study, stated, &#8220;The study is important because it enhances our understanding of human neurogenesis by revealing the role of the chromatin modifier LSD1 in regulating neuronal development, and it identifies novel downstream effectors and pathways involved in this process.&#8221;<br \/><br \/>Additionally, Dr. Pradeepa Madapaura (Group leader at Queen Mary University of London), in an email response, stated, \u201cThis elegant study by Bhavana Murilidharan\u2019s group demonstrates the mechanism through which a chromatin-modifying protein called LSD1 regulates the composition of cell type in the developing brain by regulating the expression of genes. Particularly, this study uncovers the different function of human LSD1, which could contribute to human specific brain function\u201d.<br \/><br \/>\u201cThis study will advance our understanding of human-specific brain development and provide potential opportunities to use epigenetic drugs to treat genetic disorders leading to severe neurodevelopmental disorders unique to humans,\u201d Dr. Madapaura added.<br \/><br \/>Looking ahead, Dr. Muralidharan and her team envisions the next phase of the study, aiming to uncover precise disruptions in individuals with intellectual disabilities. This endeavor holds the promise of providing valuable insights for better diagnosis and more targeted treatments, ultimately contributing to a deeper understanding of the complexities of the human brain and its disorders.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-2ba30a48 elementor-widget elementor-widget-text-editor\" data-id=\"2ba30a48\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p><strong>Journal Reference:<\/strong><br \/><a href=\"https:\/\/doi.org\/10.1093\/stmcls\/sxad088\" target=\"_blank\" rel=\"noopener\">LSD1 Regulates Neurogenesis in Human Neural Stem Cells Through the Repression of Human-Enriched Extracellular Matrix and Cell Adhesion Genes<\/a><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-5cd3664e elementor-widget elementor-widget-text-editor\" data-id=\"5cd3664e\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p><strong>Disclaimer:<\/strong><br \/>SciSoup claims no competing interest. To ensure accuracy and scientific relevance, this science blog has been reviewed by the research team involved in the study.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-419d5da e-con-full e-flex e-con e-child\" data-id=\"419d5da\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-2e92c191 section-title-style-style2 title-three-line meta-visibility-show title_position_default title_hover_border_default img_hover_animation_default meta_position_default tpg-category-position-default grid-hover-overlay-type-always tpg-el-box-border-enable tpg-border-bottom-disable elementor-widget elementor-widget-tpg-list-layout\" data-id=\"2e92c191\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"tpg-list-layout.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\n        <div class=\"rt-container-fluid rt-tpg-container 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src=\"https:\/\/scisoup.org\/in\/wp-content\/uploads\/2026\/05\/08102025-150x150.png\"\n\t\t\t\t\t\t\t class=\"rt-img-responsive\"\n\t\t\t\t\t\t\t width=\"150\"\n\t\t\t\t\t\t\t height=\"150\"\n\t\t\t\t\t\t\t alt=\"Read More, Write More: A Realistic Guide to Academic Writing\">\n\t\t\t\t\t\t\n\t\t\t\t\t\t\t\n\t\t<\/a>\n\t\t\t\t<div class=\"overlay grid-hover-content\"><\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\n\t\t\t<div class=\"post-right-content\">\n\t\t\t\t<div class=\"entry-title-wrapper\"><h3 class=\"entry-title\"><a data-id=\"1329\" href=\"https:\/\/scisoup.org\/in\/2025\/10\/08\/read-more-write-more-a-realistic-guide-to-academic-writing\/\" class=\"tpg-post-link\" target=\"_self\">Read More, Write More: A Realistic Guide to Academic Writing<\/a><\/h3><\/div>\n\t\t\t\t\t\t\t\t\t<div class=\"post-meta-tags rt-el-post-meta\">\n\t\t\t\t\t\t\t\t\t<span class=\"date\">\n\t\t\t\t<i class=\"tpg-flaticon-calendar \"><\/i>\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/scisoup.org\/in\/2025\/10\/08\/\">\n\t\t\t\t\tOctober 8, 2025\t\t\t\t<\/a>\n\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t<span class=\"categories-links\">\n\t\t\t\t<i class=\"tpg-flaticon-folder \"><\/i><a class=\"articles\" href=\"https:\/\/scisoup.org\/in\/category\/articles\/\">Articles<\/a><span class=\"rt-separator\">,<\/span><a class=\"career-insights\" href=\"https:\/\/scisoup.org\/in\/category\/career-insights\/\">Career Insights<\/a>\t\t\t<\/span>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\n\t\t\t\t\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t<\/div>\n<\/div>\n\n<div class=\"rt-col-md-12 rt-col-sm-12 rt-col-xs-12 default rt-list-item rt-grid-item\" data-id=\"1339\">\n\t<div class=\"rt-holder tpg-post-holder \">\n\t\t<div class=\"rt-detail rt-el-content-wrapper\">\n\t\t\t\t\t\t\t<div class=\"rt-img-holder tpg-el-image-wrap has-thumbnail\">\n\t\t\t\t\t<a data-id=\"1339\" href=\"https:\/\/scisoup.org\/in\/2025\/09\/03\/plants-rebuild-roots-using-geometry-not-just-genes-study\/\" class=\"tpg-post-link\" target=\"_self\">\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/scisoup.org\/in\/wp-content\/uploads\/2026\/03\/03092025-150x150.png\"\n\t\t\t\t\t\t\t class=\"rt-img-responsive\"\n\t\t\t\t\t\t\t width=\"150\"\n\t\t\t\t\t\t\t height=\"150\"\n\t\t\t\t\t\t\t alt=\"Plants Rebuild Roots Using Geometry, Not Just Genes: Study\">\n\t\t\t\t\t\t\n\t\t\t\t\t\t\t\n\t\t<\/a>\n\t\t\t\t<div class=\"overlay grid-hover-content\"><\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\n\t\t\t<div class=\"post-right-content\">\n\t\t\t\t<div class=\"entry-title-wrapper\"><h3 class=\"entry-title\"><a data-id=\"1339\" href=\"https:\/\/scisoup.org\/in\/2025\/09\/03\/plants-rebuild-roots-using-geometry-not-just-genes-study\/\" class=\"tpg-post-link\" target=\"_self\">Plants Rebuild Roots Using Geometry, Not Just Genes: Study<\/a><\/h3><\/div>\n\t\t\t\t\t\t\t\t\t<div class=\"post-meta-tags rt-el-post-meta\">\n\t\t\t\t\t\t\t\t\t<span class=\"date\">\n\t\t\t\t<i 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tpg-el-image-wrap has-thumbnail\">\n\t\t\t\t\t<a data-id=\"1321\" href=\"https:\/\/scisoup.org\/in\/2025\/05\/06\/scientists-uncover-unusual-cell-division-behind-glioblastomas-deadly-comeback-3\/\" class=\"tpg-post-link\" target=\"_self\">\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/scisoup.org\/in\/wp-content\/uploads\/2026\/01\/06052025-150x150.png\"\n\t\t\t\t\t\t\t class=\"rt-img-responsive\"\n\t\t\t\t\t\t\t width=\"150\"\n\t\t\t\t\t\t\t height=\"150\"\n\t\t\t\t\t\t\t alt=\"Scientists Uncover Unusual Cell Division Behind Glioblastoma\u2019s Deadly Comeback\">\n\t\t\t\t\t\t\n\t\t\t\t\t\t\t\n\t\t<\/a>\n\t\t\t\t<div class=\"overlay grid-hover-content\"><\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\n\t\t\t<div class=\"post-right-content\">\n\t\t\t\t<div class=\"entry-title-wrapper\"><h3 class=\"entry-title\"><a data-id=\"1321\" href=\"https:\/\/scisoup.org\/in\/2025\/05\/06\/scientists-uncover-unusual-cell-division-behind-glioblastomas-deadly-comeback-3\/\" class=\"tpg-post-link\" target=\"_self\">Scientists Uncover Unusual Cell Division Behind Glioblastoma\u2019s Deadly Comeback<\/a><\/h3><\/div>\n\t\t\t\t\t\t\t\t\t<div class=\"post-meta-tags rt-el-post-meta\">\n\t\t\t\t\t\t\t\t\t<span class=\"date\">\n\t\t\t\t<i class=\"tpg-flaticon-calendar \"><\/i>\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/scisoup.org\/in\/2025\/05\/06\/\">\n\t\t\t\t\tMay 6, 2025\t\t\t\t<\/a>\n\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t<span class=\"categories-links\">\n\t\t\t\t<i class=\"tpg-flaticon-folder \"><\/i><a class=\"articles\" href=\"https:\/\/scisoup.org\/in\/category\/articles\/\">Articles<\/a><span class=\"rt-separator\">,<\/span><a class=\"latest\" href=\"https:\/\/scisoup.org\/in\/category\/latest\/\">Latest<\/a><span class=\"rt-separator\">,<\/span><a class=\"recent-posts\" href=\"https:\/\/scisoup.org\/in\/category\/recent-posts\/\">Recent 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Undergraduates\">\n\t\t\t\t\t\t\n\t\t\t\t\t\t\t\n\t\t<\/a>\n\t\t\t\t<div class=\"overlay grid-hover-content\"><\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\n\t\t\t<div class=\"post-right-content\">\n\t\t\t\t<div class=\"entry-title-wrapper\"><h3 class=\"entry-title\"><a data-id=\"1363\" href=\"https:\/\/scisoup.org\/in\/2025\/01\/14\/navigating-internships-and-research-opportunities-in-india-ten-faqs-for-undergraduates\/\" class=\"tpg-post-link\" target=\"_self\">Navigating Internships and Research Opportunities in India: Ten FAQs for Undergraduates<\/a><\/h3><\/div>\n\t\t\t\t\t\t\t\t\t<div class=\"post-meta-tags rt-el-post-meta\">\n\t\t\t\t\t\t\t\t\t<span class=\"date\">\n\t\t\t\t<i class=\"tpg-flaticon-calendar \"><\/i>\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/scisoup.org\/in\/2025\/01\/14\/\">\n\t\t\t\t\tJanuary 14, 2025\t\t\t\t<\/a>\n\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t<span class=\"categories-links\">\n\t\t\t\t<i class=\"tpg-flaticon-folder \"><\/i><a class=\"articles\" href=\"https:\/\/scisoup.org\/in\/category\/articles\/\">Articles<\/a><span class=\"rt-separator\">,<\/span><a class=\"career-insights\" href=\"https:\/\/scisoup.org\/in\/category\/career-insights\/\">Career Insights<\/a><span class=\"rt-separator\">,<\/span><a class=\"recent-posts\" href=\"https:\/\/scisoup.org\/in\/category\/recent-posts\/\">Recent Posts<\/a><span class=\"rt-separator\">,<\/span><a class=\"spotlight\" href=\"https:\/\/scisoup.org\/in\/category\/spotlight\/\">Spotlight<\/a>\t\t\t<\/span>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\n\t\t\t\t\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t<\/div>\n<\/div>\n\n<div class=\"rt-col-md-12 rt-col-sm-12 rt-col-xs-12 default rt-list-item rt-grid-item\" data-id=\"1358\">\n\t<div class=\"rt-holder tpg-post-holder \">\n\t\t<div class=\"rt-detail rt-el-content-wrapper\">\n\t\t\t\t\t\t\t<div class=\"rt-img-holder tpg-el-image-wrap has-thumbnail\">\n\t\t\t\t\t<a data-id=\"1358\" href=\"https:\/\/scisoup.org\/in\/2025\/01\/12\/scientists-discover-a-new-host-protein-that-could-halt-viral-replication\/\" class=\"tpg-post-link\" target=\"_self\">\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/scisoup.org\/in\/wp-content\/uploads\/2026\/05\/12-01-2025-150x150.png\"\n\t\t\t\t\t\t\t class=\"rt-img-responsive\"\n\t\t\t\t\t\t\t width=\"150\"\n\t\t\t\t\t\t\t height=\"150\"\n\t\t\t\t\t\t\t alt=\"Scientists Discover a New Host Protein That Could Halt Viral Replication\">\n\t\t\t\t\t\t\n\t\t\t\t\t\t\t\n\t\t<\/a>\n\t\t\t\t<div class=\"overlay grid-hover-content\"><\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\n\t\t\t<div class=\"post-right-content\">\n\t\t\t\t<div class=\"entry-title-wrapper\"><h3 class=\"entry-title\"><a data-id=\"1358\" href=\"https:\/\/scisoup.org\/in\/2025\/01\/12\/scientists-discover-a-new-host-protein-that-could-halt-viral-replication\/\" class=\"tpg-post-link\" target=\"_self\">Scientists Discover a New Host Protein That Could Halt Viral Replication<\/a><\/h3><\/div>\n\t\t\t\t\t\t\t\t\t<div class=\"post-meta-tags rt-el-post-meta\">\n\t\t\t\t\t\t\t\t\t<span class=\"date\">\n\t\t\t\t<i class=\"tpg-flaticon-calendar \"><\/i>\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/scisoup.org\/in\/2025\/01\/12\/\">\n\t\t\t\t\tJanuary 12, 2025\t\t\t\t<\/a>\n\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t<span class=\"categories-links\">\n\t\t\t\t<i class=\"tpg-flaticon-folder \"><\/i><a class=\"articles\" href=\"https:\/\/scisoup.org\/in\/category\/articles\/\">Articles<\/a><span class=\"rt-separator\">,<\/span><a class=\"latest\" href=\"https:\/\/scisoup.org\/in\/category\/latest\/\">Latest<\/a><span class=\"rt-separator\">,<\/span><a class=\"recent-posts\" href=\"https:\/\/scisoup.org\/in\/category\/recent-posts\/\">Recent Posts<\/a>\t\t\t<\/span>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\n\t\t\t\t\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t<\/div>\n<\/div>\n\n<div class=\"rt-col-md-12 rt-col-sm-12 rt-col-xs-12 default rt-list-item rt-grid-item\" 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class=\"rt-holder tpg-post-holder \">\n\t\t<div class=\"rt-detail rt-el-content-wrapper\">\n\t\t\t\t\t\t\t<div class=\"rt-img-holder tpg-el-image-wrap has-thumbnail\">\n\t\t\t\t\t<a data-id=\"1377\" href=\"https:\/\/scisoup.org\/in\/2024\/08\/31\/commemorating-dr-ramalingaswami-the-fellowship-empowering-indian-scientists-2\/\" class=\"tpg-post-link\" target=\"_self\">\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/scisoup.org\/in\/wp-content\/uploads\/2026\/05\/31-08-2024-150x150.png\"\n\t\t\t\t\t\t\t class=\"rt-img-responsive\"\n\t\t\t\t\t\t\t width=\"150\"\n\t\t\t\t\t\t\t height=\"150\"\n\t\t\t\t\t\t\t alt=\"Commemorating Dr. Ramalingaswami: The Fellowship Empowering Indian Scientists\">\n\t\t\t\t\t\t\n\t\t\t\t\t\t\t\n\t\t<\/a>\n\t\t\t\t<div class=\"overlay grid-hover-content\"><\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\n\t\t\t<div class=\"post-right-content\">\n\t\t\t\t<div class=\"entry-title-wrapper\"><h3 class=\"entry-title\"><a data-id=\"1377\" 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class=\"overlay grid-hover-content\"><\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\n\t\t\t<div class=\"post-right-content\">\n\t\t\t\t<div class=\"entry-title-wrapper\"><h3 class=\"entry-title\"><a data-id=\"1450\" href=\"https:\/\/scisoup.org\/in\/2024\/07\/06\/tapping-earths-heat-indias-next-big-leap-in-clean-energy\/\" class=\"tpg-post-link\" target=\"_self\">Tapping Earth&#8217;s Heat: India\u2019s Next Big Leap In Clean Energy<\/a><\/h3><\/div>\n\t\t\t\t\t\t\t\t\t<div class=\"post-meta-tags rt-el-post-meta\">\n\t\t\t\t\t\t\t\t\t<span class=\"date\">\n\t\t\t\t<i class=\"tpg-flaticon-calendar \"><\/i>\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/scisoup.org\/in\/2024\/07\/06\/\">\n\t\t\t\t\tJuly 6, 2024\t\t\t\t<\/a>\n\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t<span class=\"categories-links\">\n\t\t\t\t<i class=\"tpg-flaticon-folder \"><\/i><a class=\"articles\" href=\"https:\/\/scisoup.org\/in\/category\/articles\/\">Articles<\/a><span class=\"rt-separator\">,<\/span><a class=\"recent-posts\" 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